DUKE SURGERY RESEARCH CENTRAL: AN OPEN-SOURCE WEB APPLICATION FOR THE IMPROVEMENT OF COMPLIANCE WITH RESEARCH REGULATION

Duke Surgery Research Central: an open-source Web application for the improvement of compliance with research regulation

Abstract Background Although regulatory compliance in academic research is enforced by law to ensure high quality and safety to participants, its implementation is frequently hindered by cost and logistical barriers.In order to decrease these barriers, we have developed a Web-based application, Duke Surgery Research Central (DSRC), to monitor and s

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USP14: Structure, Function, and Target Inhibition

Ubiquitin-specific protease 14 (USP14), a deubiquitinating enzyme (DUB), is associated with proteasomes and exerts a dual function in regulating protein degradation.USP14 lorenametaute.com protects protein substrates from degradation by removing ubiquitin chains from proteasome-bound substrates, whereas promotes protein degradation by activating th

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